Here’s Everything You Should Know About Fc Block in Flow Cytometry

What is the Importance of Using an FcR Blocker During Cell Separation Procedures?

During the cell separation process, it is imperative to prevent non-specific binding to ensure the purity of your cells which will, in turn, lead to optimum results. Fc receptors (FcR) on cells have a high affinity for the Fc region of antibodies. To prevent the non-specific binding of antibodies to cells, it is advisable to add an FcR blocker to your sample prior to cell separation. To prevent the nonspecific binding of the antibodies, it is recommended to add an FcR blocker to your sample before the cell separation.

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